177477-96-2

Upstream product

• 174298-71-6 N-[3-(tert-Butyl-diphenyl-silanyloxymethyl)-2,4-dimethyl-phenyl]-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-N-methyl-acetamide 
• 174298-70-5 N-[3-(tert-Butyl-diphenyl-silanyloxymethyl)-2,4-dimethyl-phenyl]-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetamide 
• 174298-68-1 tert-Butyl-(2,6-dimethyl-3-nitro-benzyloxy)-diphenyl-silane 
• 174298-69-2 3-amino-1-(tert-butyldiphenylsilyloxymethyl)-2,6-dimethylbenzene 
• 82617-30-9 (2,6-dimethyl-3-nitrophenyl)methyl acetate 
• 82617-29-6 2,6-dimethyl-3-nitrobenzene-1-methanol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 62346-87-6 2,6-dimethylbenzyl acetate 
• 62285-58-9 2,6-dimethylbenzyl alcohol 
• 174298-72-7 3-(N-Glycyl-N-methylamino)-1-(tert-butyldiphenylsilyloxymethyl)-2,6-dimethylbenzene 
• 179627-11-3 4-(methylcarbamoyl)cinnamic acid 

Downstream Products

• 177477-46-2 4-[2,6-dimethyl-3-[N-[4-(methylcarbamoyl)cinnamoylglycyl]-N-methylamino]benzyloxy]-2-mercapto-1-methyl-1H-benzimidazole 
• 177478-40-9 3-[2,6-Dimethyl-3-[N-[4-(methylcarbamoyl)-cinnamoylglycyl]-N-methylamino]benzyloxy]-2-amino-N-methylaniline 
• 177477-98-4 1-chloromethyl-2,6-dimethyl-3-[N-[4-(methylcarbamoyl)cinnamoylglycyl]-N-methylamino]benzene 
• 177477-97-3 1-Hydroxymethyl-2,6-dimethyl-3-[N-[4-(methylcarbamoyl)-cinnamoylglycyl]-N-methylamino]benzene 

Relevant academic research and scientific papers

A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 3. Discovering bioisosteres of the imidazo[1,2-a]pyridine moiety

Recently we reported on overcoming the species difference of our first orally active non-peptide bradykinin (BK) B2 receptor antagonists, incorporating an 8-[[3-(N-acylglycyl-N-methylamino)-2,6-dichlorobenzyl]oxy]- 3-halo-2-methylimidazo[1,2-α]