177481-90-2

Upstream product

• 155720-51-7 1-(2-ethynylphenyl)-3-(trimethylsilyl)prop-2-yn-1-ol 
• 74-88-4 methyl iodide 

Downstream Products

• 177482-21-2 Trifluoro-methanesulfonic acid 2-[2-(1-methoxy-3-trimethylsilanyl-prop-2-ynyl)-phenylethynyl]-cyclohex-2-en-(Z)-ylidenemethyl ester 
• 177482-23-4 (Z)-<2-<<2-(1-Methoxy-2-propynyl)phenyl>ethynyl>-2-cyclohexen-1-ylidene>methyl trifluoromethanesulfonate 
• 177481-92-4 2-[3-[2-(1-Methoxy-3-trimethylsilanyl-prop-2-ynyl)-phenyl]-prop-2-yn-(E)-ylidene]-cyclohexanone 

Relevant academic research and scientific papers

Synthesis of 6-/10-membered ring analogs of the dienediyne core of the neocarzinostatin chromophore by palladium(0)-mediated ring-closure reactions

A strategy for the synthesis of the benzo-annulated bicyclic dienediyne analogs 46 and 48 of the DNA-cleaving natural product neocarzinostatin chromophore was developed. 2-Formylcyclohexanone (9) was converted stereoselectively first into the mono(enol tr