1775-89-9Relevant articles and documents
Selective C-H Olefination of Indolines (C5) and Tetrahydroquinolines (C6) by Pd/S,O-Ligand Catalysis
Jia, Wen-Liang,Westerveld, Nick,Wong, Kit Ming,Morsch, Thomas,Hakkennes, Matthijs,Naksomboon, Kananat,Fernández-Ibá?ez, M. ángeles
supporting information, p. 9339 - 9342 (2019/11/21)
Herein, we report a highly selective C-H olefination of directing-group-free indolines (C5) and tetrahydroquinolines (C6) by Pd/S,O-ligand catalysis. In the presence of the S,O-ligand, a wide range of challenging indolines, tetrahydroquinolines, and olefins was efficiently olefinated under mild reaction conditions. The synthetic potential of this methodology was demonstrated by the efficient olefination of several indoline-based natural products.