17752-36-2Relevant academic research and scientific papers
The hydroxylation of Δ5-androstenes by Cephalosporium aphidicola
Bensasson, Caroline M.,Hanson, James R.,Hunter, A. Christy
, p. 2355 - 2358 (2007/10/03)
Whereas the major hydroxylation product of 3β-hydroxy-5α-androstan- 17-one by Cephalosporium aphidicola is the 11α-alcohol, the presence of a Δ5-double bond in the substrate leads to non-stereospecific allylic hydroxylation at C-7. Hydroxylation at C-11 became a minor transformation and there was no detectable hydroxylation at C-14.
The hydroxylation of some 13α-methylsteroids by Cephalosporium aphidicola
Boynton, Juliette,Hanson, James R.,Hunter, A. Christy
, p. 951 - 956 (2007/10/03)
The Fungus, Cephalosporium aphidicola, has been shown to hydroxylate 5α,13α-androstan-3,17-dione and the 3β-alcohol at the C-1α and C-7α positions, whereas the corresponding compounds in the normal 13β-methyl series are hydroxylated at the C-11α and C-14α positions. Both series were hydroxylated at the 5α position. There was some epimerization of the axial 3α-alcohols to the equatorial 3β-epimers.
