177561-15-8

Basic information

• Product Name: 2-(2-chlorophenyl)-4-(4-fluorophenyl)-5-(4-methylthiophenyl)thiazole
• Synonyms: 2-(2-chlorophenyl)-4-(4-fluorophenyl)-5-(4-methylthiophenyl)thiazole
• CAS NO: 177561-15-8
• Molecular Weight: 411.951
• Mol File: 177561-15-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(2-chlorophenyl)-4-(4-fluorophenyl)-5-(4-methylthiophenyl)thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-chlorophenyl)-4-(4-fluorophenyl)-5-(4-methylthiophenyl)thiazole(177561-15-8)
• EPA Substance Registry System: 2-(2-chlorophenyl)-4-(4-fluorophenyl)-5-(4-methylthiophenyl)thiazole(177561-15-8)

Safety Data

• Hazardous Substances Data: 177561-15-8(Hazardous Substances Data)

Upstream product

• 15717-17-6 2-chlorothiobenzamide 
• 71006-38-7 1-(4-fluorophenyl)-2-(4-methylthiophenyl)-2-bromoethanone 
• 36187-57-2 1-(4-fluorophenyl)-2-(4-(methylthio)phenyl)ethanone 
• 873-32-5 2-Chlorobenzonitrile 

Downstream Products

• 177560-23-5 2-(2-chlorophenyl)-4-(4-fluorophenyl)-5-[(4-methylsulfonyl)phenyl]thiazole 

Relevant articles and documents

Design and synthesis of sulfonyl-substituted 4,5-diarylthiazoles as selective cyclooxygenase-2 inhibitors

A series of novel sulfone substituted 4,5-diarylthiazoles have been synthesized and evaluated for their inhibition of the two isoforms of human cyclooxygenase (COX-1 and COX-2). This series displays exceptionally selective COX-2 inhibition.