Cas 177611-40-4,[3-(2-Amino-phenyl)-3-oxo-propyl]-isopropyl-carbamic acid benzyl ester

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Check Digit Verification of cas no

The CAS Registry Mumber 177611-40-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,7,6,1 and 1 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 177611-40:
(8*1)+(7*7)+(6*7)+(5*6)+(4*1)+(3*1)+(2*4)+(1*0)=144
144 % 10 = 4
So 177611-40-4 is a valid CAS Registry Number.

177611-40-4Upstream product

177611-40-4Downstream Products

213129-96-5 {2-[4-Hydroxy-4-(2-hydroxy-ethyl)-3,13-dioxo-3,4,12,13-tetrahydro-1H-2-oxa-6,12a-diaza-dibenzo[b,h]fluoren-11-yl]-ethyl}-isopropyl-carbamic acid benzyl ester

177611-40-4Relevant academic research and scientific papers

Synthesis and antitumor activity of 7-substituted 20(RS)-camptothecin analogues

Jew, Sang-Sup,Kim, Hee-Jin,Kim, Myoung Goo,Roh, Eun-Young,Cho, Youn-Sang,Kim, Joon-Kyum,Cha, Kyung-Hoe,Lee, Kang-Keun,Han, Hyun-Jung,Choi, Jae-Young,Lee, Heesoon

, p. 845 - 848 (2007/10/03)

Novel water-soluble camptothecin analogues with excellent antitumor activity have been designed and synthesized by total synthesis. The analogues were evaluated for cytotoxic activity against five tumor cell lines. The most potent analogue 6c exhibited significant antitumor activity at wider range of doses as compared with camptothecin (T/C 243% at 70 mg/kg; T/C 150% at 8.75-140 mg/kg).

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