177611-98-2Relevant academic research and scientific papers
Synthesis and in vitro cytotoxicity of (RS)-20-desethyl-20-substituted camptothecin analogues
Jew, Sang-Sup,Kim, Myoung Goo,Kim, Hee-Jin,Roh, Eun-Young,Cho, Youn-Sang,Kim, Joon-Kyum,Cha, Kyung-Hoe,Lee, Kang-Keun,Han, Hyun-Jung,Lee, Heesoon
, p. 849 - 852 (2007/10/03)
Sixteen (RS)-20-desethyl-20-substituted camptothecin analogues were designed and prepared by total synthesis. These analogues were evaluated for cytotoxic activity against five tumor cell lines. The cytotoxic activity of compound 14f was shown to be comparable to that of camptothecin.
