17762-03-7Relevant academic research and scientific papers
INDOLE AND AZAINDOLE HALOALLYLAMINE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF
-
Paragraph 0327, (2017/09/05)
The present invention relates to novel compounds which are capable of inhibiting certain amine oxidase enzymes. These compounds are useful for treatment of a variety of indications, e.g., fibrosis, cancer and/or angiogenesis in human subjects as well as i
Synthesis of N,N-Dioxopyridazines
Rozen, Shlomo,Shaffer, Avshalom
supporting information, p. 4707 - 4709 (2017/09/23)
Despite many efforts, one of the smallest heterocycles containing two nitrogen atoms, pyridazine, could not be converted to its N,N-dioxide (see, however, Nakadate et al. Chem. Pharm. Bull. 1970, 18, 1211-1218). HOF·CH3CN, made easily from diluted fluorine, was able to accomplish this task in a fast reaction with good yields.
