17763-65-4

Upstream product

• 129112-25-0 2-(trifluoromethanesulfonyl)oxy-bromobenzene 
• 98-80-6 phenylboronic acid 
• 129112-26-1 2-iodophenyltrifluoromethanesulfonic acid 
• 589-87-7 1,4-bromoiodobenzene 

Downstream Products

• 84-15-1 o-terphenyl 
• 606-97-3 2-benzyl-1,1'-biphenyl 
• 1009807-64-0 (R)-(+)-biphenyl-2-yl-(1-phenylethyl)amine 
• 52648-48-3 N-(phenylmethyl)-(1,1'-biphenyl)-2-amine 
• 19853-10-2 2-(biphenyl-2-yl)acetonitrile 
• 1234674-98-6 N-(9H-fluoren-9-ylidene)-2,6-diisopropylaniline 
• 10271-65-5 2-(phenylethynyl)-1,1'-biphenyl 
• 13885-09-1 [1,1′-biphenyl]-2-yldiphenylphosphane 
• 1031-13-6 5-phenyl-5H-dibenzophosphole-5-oxide 
• 1942-82-1 [1,1′-biphenyl]-2-yldimethylphosphine oxide 
• 1203-68-5 2-Phenylbenzaldehyde 

Relevant academic research and scientific papers

Rapid Access to Bi- and Tri-Functionalized Dibenzofurans and their Application in Selective Suzuki–Miyaura Cross Coupling Reactions

Syntheses of 1,2-, 1,3-, 1,4-, 1,8-, 2,4-, 3,4-, 4,8-, 1,2,4-, 1,2,8- and 1,3,4-functionalized dibenzofurans in few steps with good to excellent yields starting from dibenzofuran-1-ol or -4-ol are presented. These rapidly accessible bi- or tri-functionalized building blocks are of great interest for the synthesis of bioactive substances or functional material development. Furthermore, for intermediates containing both a bromine and a triflate moiety, a selective mono-substitution by means of Suzuki–Miyaura reaction (SMR) is described.

PRODUCING METHOD OF MONO-COUPLING BODY

The present invention provides a producing method of a compound represented by the general formula (5): R1-Ar-X, which is characterized by bringing an aromatic compound represented by the general formula (1): R1-Ar-X' (in the formula, Ar, X and X', R1 has a definition the same as the specification and claims) into reaction with an organic boron compound represent by the general formula (2) to (4) in water and organic solvent, in the presence of water-soluble palladium and base. The producing method of this invention is capable of suppressing subgeneration of dicoupling body when providing a compound with two leaving groups to coupling reaction, and capable of selectively and easily obtain a mono-coupling body.

CONNECTIONS TO THE DIRECTED ORTHO METALATION STRATEGY. Pd(0)-CATALYZED CROSS COUPLING OF ARYL BORONIC ACIDS WITH ARYL TRIFLATES

A new and general Pd(0)-catalyzed cross coupling reaction of aryl boronic acids with aryl triflates to give biaryls (Scheme 1) is reported.