177659-26-6Relevant articles and documents
Synthesis of benzo-fused lactams and lactones via Ru(II)-catalyzed cycloaddition of amide- and ester-tethered α,ω-diynes with terminal alkynes: Electronic directing effect of internal conjugated carbonyl group
Yamamoto, Yoshihiko,Kinpara, Keisuke,Saigoku, Tomoaki,Nishiyama, Hisao,Itoh, Kenji
, p. 1287 - 1294 (2007/10/03)
In the presence of a catalytic amount of Cp*RuCl(cod), 1,6- and 1,7-diynes connected by an amide or an ester tether underwent cycloaddition with terminal alkynes at room temperature to give rise to cycloadducts in 40-93% yields with 63 : 37-83 : 17 regioisomer ratios.