177723-83-0Relevant academic research and scientific papers
Synthesis of αβ-unsaturated trifluoromethyl ketones from 4-Dimethylamino-1,1,1-trifluorobut-3-ene-2-one by addition of grignard reagents
Andrew, Rebecca J.,Mellor, John M.
, p. 7261 - 7266 (2000)
Enaminones are available by reaction of 4-ethoxy-1,1,1-trifluorobut-3-ene-2-one with amines such as dimethylamine and they react with Grignard reagents to give αβ-unsaturated trifluoromethyl ketones in good yield by 1,4-addition followed by elimination. The generality of this procedure is contrasted with reactions based either on the use of organolithium nucleophiles, or the use of 4-alkoxy-αβ-unsaturated trifluoromethyl ketones as electrophilic partners. (C) 2000 Elsevier Science Ltd.
Reactions of β-alkoxyvinyl trifluoromethyl ketones with terminal alkynes - Reagent-controlled regioselectivity addition reactions
Zhu, Shizheng,Jin, Guifang,Jiang, Hulling
, p. 2127 - 2131 (2007/10/03)
Reactions of β-alkoxyvinyl trifluoromethyl ketones ROCH=CHCOCF 3 (1, R = Et, Me2CHCH2), and their cyclic analogues 4-trifluoroacetyl-2,3-dihydrofuran (2a) and 5-trifluoroacetyl-3,4- dihydro-2H-pyran (2b), with terminal alk
Synthesis of new halo-containing acetylenes and their application to the synthesis of azoles
Martins, Marcos A.P.,Emmerich, Daniel J.,Pereira, Claudio M.P.,Cunico, Wilson,Rossato, Marcelo,Zanatta, Nilo,Bonacorso, Helio G.
, p. 4935 - 4938 (2007/10/03)
The convenient synthesis of ten halo- and an isoxazole-containing acetylenes from the reaction of acetylenes with n-butyl lithium and subsequent reaction with an electrophile agent (ethyl trichloroacetate, ethyl dichloroacetate, trifluoroacetic anhydride,
Synthesis of 6-substituted 1,1,1-trifluoro-3-hexen-5-yn-2ones
Sanin,Nenaidenko,Denisenko,Smolko,Balenkova
, p. 209 - 211 (2007/10/03)
(E)-4-Dimethylamino-1,1,1-trifluoro-3-buten-2-one stereospecifically reacts with lithium acetylides with replacement of amino group to afford E-isomers of trifluoro-containing conjugated enynones RC≡CCH=CHCOCF3.
