17773-41-0

Basic information

• Product Name: 2-hydroxy-4-(methylthio)butyronitrile
• Synonyms: 2-hydroxy-4-(methylthio)butyronitrile;2-Hydroxy-4-(methylmercapto)-butyronitrile;2-Hydroxy-4-(methylthio)butanenitrile
• CAS NO: 17773-41-0
• Molecular Formula: C₅H₉NOS
• Molecular Weight: 131.19606
• EINECS: 241-756-3
• Mol File: 17773-41-0.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 279.6°Cat760mmHg
• Flash Point: 122.9°C
• Appearance: /
• Density: 1.128g/cm³
• Vapor Pressure: 0.00048mmHg at 25°C
• Refractive Index: 1.507
• PKA: 11.01±0.20(Predicted)
• Water Solubility: 110g/L at 25℃
• CAS DataBase Reference: 2-hydroxy-4-(methylthio)butyronitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-4-(methylthio)butyronitrile(17773-41-0)
• EPA Substance Registry System: 2-hydroxy-4-(methylthio)butyronitrile(17773-41-0)

Safety Data

• Hazardous Substances Data: 17773-41-0(Hazardous Substances Data)

Usage

Hazard

A poison by ingestion and skin contact. A moderate skin irritant.

InChI:InChI=1/C5H9NOS/c1-8-3-2-5(7)4-6/h5,7H,2-3H2,1H3

Upstream product

• 3268-49-3 3-(methylsulfenyl)propanal 
• 143-33-9 sodium cyanide 
• 74-93-1 methylthiol 
• 5809-59-6 3-cyano-3-hydroxy-1-propene 
• 773837-37-9 sodium cyanide 
• 119353-03-6 3-(methylselenyl)-propanal 
• 74-90-8 hydrogen cyanide 

Downstream Products

• 49540-21-8 α-hydroxy-4-methylthiobutyramide 
• 583-91-5 2-hydroxy 4-methylthiobutyric acid 
• 63302-72-7 2-hydroxy-4-methylthiobutyric acid ammonium salt 
• 59-51-8 DL-methionine 
• 13253-44-6 5-[2-(methylthio)ethyl]imidazolidine-2,4-dione 
• 94087-93-1 2-hydroxy-4-methylmercaptobutyric acid potassium salt 
• 3198-47-8 α-amino-γ-methylmercapto-butyronitrile 
• 19298-72-7 DL-methionine amide 
• 7349-78-2 DD/LL/LD/DL-methionylmethionine 
• 89033-45-4 hydantoin amide 
• 7349-78-2 N-L-methionyl-L-methionine 
• 36963-02-7 3,6-bis[2-(methylthio)ethyl]-2,5-piperazinedione 

Relevant articles and documents

METHOD FOR MANUFACTURING METHIONINE

An object of the present invention is to provide a method for manufacturing methionine capable of achieving an improvement in ammonia removal efficiency. The manufacturing method of the present invention comprises a removal step of supplying a liquid containing a methionine salt, which is obtained by reacting 3-methylmercaptopropionaldehyde and hydrocyanic acid, or a compound obtained by reacting 3-methylmercaptopropionaldehyde and hydrocyanic acid, with carbon dioxide and ammonia to obtain a liquid containing 5-(2-methylmercaptoethyl)hydantoin and then hydrolyzing the 5-(2-methylmercaptoethyl)hydantoin, to a diffusion tower from an upper portion thereof while supplying a stripping gas to the diffusion tower from a lower portion thereof to remove ammonia contained in the liquid through stripping, and the stripping gas contains a process gas generated in a process of manufacturing methionine.

STORAGE-STABLE FORM OF 3-METHYLTHIOPROPIONALDEHYDE

A chemical compound of formula (I), and specific compositions including 3-methylthiopropionaldehyde, 3-methylthiopropane-1,1-diol, a compound of formula I and water, and processes for producing same and also the use of same may be used for the production of 2-hydroxy-4-(methylthio)butyronitrile, methionine hydantoin, methionine. Protected forms may be used for the storage and/or transport of 3-methylthiopropionaldehyde.

METHOD FOR PREPARING METHIONINE

The present invention relates to a method for preparing methionine or methionine salts. In particular, the invention describes the step of preparing 2-hydroxy-4-(methylthio)butyronitrile (MMP-CN) from 3-methylthiopropanal (MMP) and hydrogen cyanide (HCN) in the presence of ammonia by bringing a gaseous mixture comprising HCN and ammonia into contact with MMP.