177742-15-3

Basic information

• Product Name: (2S,5R)-1-{2-[(S)-2-Acetylsulfanyl-3-(4-chloro-phenyl)-propionylamino]-acetyl}-5-(2-hydroxy-phenyl)-pyrrolidine-2-carboxylic acid ethyl ester
• Synonyms: (2S,5R)-1-{2-[(S)-2-Acetylsulfanyl-3-(4-chloro-phenyl)-propionylamino]-acetyl}-5-(2-hydroxy-phenyl)-pyrrolidine-2-carboxylic acid ethyl ester
• CAS NO: 177742-15-3
• Molecular Weight: 533.045
• Mol File: 177742-15-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,5R)-1-{2-[(S)-2-Acetylsulfanyl-3-(4-chloro-phenyl)-propionylamino]-acetyl}-5-(2-hydroxy-phenyl)-pyrrolidine-2-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,5R)-1-{2-[(S)-2-Acetylsulfanyl-3-(4-chloro-phenyl)-propionylamino]-acetyl}-5-(2-hydroxy-phenyl)-pyrrolidine-2-carboxylic acid ethyl ester(177742-15-3)
• EPA Substance Registry System: (2S,5R)-1-{2-[(S)-2-Acetylsulfanyl-3-(4-chloro-phenyl)-propionylamino]-acetyl}-5-(2-hydroxy-phenyl)-pyrrolidine-2-carboxylic acid ethyl ester(177742-15-3)

Safety Data

• Hazardous Substances Data: 177742-15-3(Hazardous Substances Data)

Upstream product

• 177741-59-2 (S)-2-tert-Butoxycarbonylamino-5-(2-methoxymethoxy-phenyl)-5-oxo-pentanoic acid ethyl ester 
• 177741-76-3 (2S,5R)-5-(2-Hydroxy-phenyl)-pyrrolidine-2-carboxylic acid ethyl ester 
• 177741-67-2 (S)-5-(2-Hydroxy-phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylic acid ethyl ester 
• 146746-34-1 2-(methoxy)methoxyphenylmagnesium bromide 
• 144978-35-8 (S)-ethyl N-tert-butoxycarbonylpyroglutamate 
• 14173-39-8 p-chlorophenylalanine 
• 177741-56-9 (S)-2-Acetylsulfanyl-3-(4-chloro-phenyl)-propionic acid 

Relevant articles and documents

Design of orally active dual inhibitors of neutral endopeptidase and angiotensin-converting enzyme with long duration of action

Mercaptoacyl dipeptides, containing a glycine linked to a C-terminal 5- phenylproline, have been synthesized in order to obtain new highly efficient dual inhibitors of the two zinc metallopeptidases, neutral endopeptidase (NEP) and angiotensin-converting