17783-69-6

Usage

Uses

Used in Organic Synthesis:
2-Indanyl p-toluenesulfonate is used as a reagent in organic synthesis for its ability to undergo substitution reactions with other electrophilic compounds. This property allows it to be a key component in the formation of various esters, ethers, and amides, contributing to its status as a versatile building block in organic chemistry.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2-Indanyl p-toluenesulfonate serves as an intermediate, playing a crucial role in the synthesis of various medicinal compounds. Its reactivity and structural features make it suitable for the development of new drugs and the improvement of existing ones.
Used as a Catalyst in Chemical Reactions:
2-Indanyl p-toluenesulfonate has demonstrated potential as an effective catalyst in certain chemical reactions. Its catalytic properties can enhance the efficiency and selectivity of reactions, which is particularly important in the synthesis of complex organic molecules and specialty chemicals.

InChI:InChI=1/C16H16O3S/c1-12-6-8-16(9-7-12)20(17,18)19-15-10-13-4-2-3-5-14(13)11-15/h2-9,15H,10-11H2,1H3

Upstream product

• 4254-29-9 indan-2-ol 
• 98-59-9 p-toluenesulfonyl chloride 
• 52148-02-4 1-bromo-indan-2-ol 

Downstream Products

• 81887-53-8 indan-2-yl methyl ether 
• 104-15-4 toluene-4-sulfonic acid 
• 95-13-6 1-indene 
• 78370-70-4 2-ethoxyindan 
• 24329-96-2 2-iodoindane 
• 33237-87-5 (4-Chloro-phenyl)-indan-2-yl-amine 
• 7255-72-3 4-chloroaniline p-toluenesulfonate 
• 33237-91-1 N-(4-methoxyphenyl)-2,3-dihydro-1H-inden-2-amine 
• 14034-69-6 Toluene-4-sulfonic acid; compound with 4-methoxy-phenylamine 
• 33237-72-8 indan-2-yl anilide 
• 14034-57-2 anilinium p-tolylsulfonate 
• 139062-79-6 isobutyl N-[1-(indan-2-yl)-piperid-4-yl]-N-methylcarbamate fumarate 
• 929713-41-7 ethyl 3-(4-(2,3-dihydro-1H-inden-2-yloxy)phenyl)-3-(5-methyloxazol-2-yl)propanoate 
• 929712-61-8 (+/-)ethyl 3-(3,5-difluorophenyl)-3-(4-(2,3-dihydro-1H-inden-2-yloxy)phenyl)propanoate 

Relevant academic research and scientific papers

Stereospecific Nickel-Catalyzed Reductive Cross-Coupling of Alkyl Tosylate and Allyl Alcohol Electrophiles

The stereospecific cross-coupling of easily accessed electrophiles holds significant promise in the construction of C-C bonds. Herein, we report a nickel-catalyzed reductive coupling of allyl alcohols with chiral, nonracemic alkyl tosylates. This cross-coupling delivers valuable allylation products with high levels of stereospecificity across a range of substrates. The catalytic system consists of a simple nickel salt in conjunction with a commercially available reductant and importantly represents a rare example of a cross-coupling involving the C-O bonds of two electrophiles.

Directionality of Proton Transfer in Solutions. Three Systems of Known Angularity

Three compounds were synthesized each possessing rigid carbon frameworks that hold an oxygen base near a mobile C-H proton in well-defined angular and distance relationships: 2-iodo-4-hydroxyindan, endo-5-hydroxybicycloheptan-2-one, and endo-2-hydroxy-exo-6-bromomethylheptane.Effective proton transfer was detected with the second and third compounds but not the first.The data suggest that C-to-O proton transfer with severely bent O/H/C angles (106 deg) is permissible if the O-H distance is less than the sum of the van der Waals radii. "Long distance" catalysis at active sites of enzymes appears unlikely.