177839-91-7

Upstream product

• 177840-03-8 N-(N'-benzyl-N'-methylglycyl)-(S)-prolinol 
• 37429-48-4 N-methyl-N-benzylglycine 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 
• 38074-72-5 (S)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid methyl ester 
• 2577-48-2 methyl (2S)-pyrrolidine carboxylate 
• 225645-11-4 1-(N-benzyl-N-methylglycyl)-(S)-proline methyl ester 

Relevant academic research and scientific papers

Synthesis and utilization of a novel glycine derived chiral precursor, based on a recyclable L-prolinol auxiliary, for the enantioselective preparation of α-amino acids and their N-methyl derivatives

α-Amino acids and their N-methyl derivatives are synthesized in fairly high optical purity employing a new glycine derived template based on a recyclable L-prolinol chiral auxiliary.

Photoinduced electron transfer (PET) promoted oxidative activation of 1- (N-benzyl-N-methylglycyl)-(S)-prolinol: Development of novel strategies towards enantioselective syntheses of α-amino acids, their N-methyl derivatives and α-hydroxy acids employing

PET activation of 1-(N-benzyl-N-methylglycyl)-(S)-prolinol (1) in dry acetonitrile, utilizing 1,4-dicyanonaphthalene (DCN) as a light-harvesting electron-acceptor and methyl viologen (MV++) as an electron-transfer mediator, leads to the formati

Synthesis and Utilisation of Chiral 3-N- Benzyl-N-methylaminoperhydropyrrolo-[2,1-c][1,4]oxazin-4-one as a Novel Precursor for the Enantioselective Synthesis of α-Amino Acids and Their N-Methyl Derivatives

α-Amino acids and their N-methyl derivatives are synthesised in good optical purity by the nucleophilic alkylation of chiral 3-N-benzyl-N-methylaminoperhydropyrrolo[2,1-c][1,4]oxazin-4-one (1). The chiral auxiliary, L-prolinol, is isolated in recyclable f