17784-47-3

Usage

Uses

Used in Fluorescent Probes:
Acridine Hydrochloride is used as a fluorescent compound for the synthetic preparation of fluorescent probes. Its strong fluorescence property allows it to be utilized in the development of probes that can be used in various research and diagnostic applications, such as detecting specific molecules or monitoring biological processes.
Used in Pharmaceutical Industry:
Acridine Hydrochloride is used as an active pharmaceutical ingredient for the treatment of certain parasitic infections, particularly those caused by trypanosomes, such as African sleeping sickness and Chagas disease. Its ability to intercalate into DNA and disrupt the replication process makes it an effective agent against these parasites.
Used in Research and Development:
Acridine Hydrochloride is used as a research tool in various scientific fields, including biochemistry, molecular biology, and pharmacology. Its interaction with DNA and other biological molecules makes it a valuable compound for studying the mechanisms of action of various drugs and understanding the structure and function of DNA.
Used in Dye Manufacturing:
Acridine Hydrochloride is used as a starting material in the synthesis of various dyes and pigments, particularly those with fluorescent properties. These dyes find applications in a wide range of industries, such as textiles, plastics, and printing inks, where their bright and vibrant colors are highly desirable.

InChI:InChI=1/C13H9N.ClH/c1-3-7-12-10(5-1)9-11-6-2-4-8-13(11)14-12;/h1-9H;1H

Upstream product

• 260-94-6 acridine 

Downstream Products

• 39676-43-2 5-acridin-9-yl-3-phenyl-thiazolidine-2,4-dione 
• 39676-41-0 5-acridin-9-yl-3-phenyl-2-thioxo-thiazolidin-4-one 
• 21923-37-5 9-(4'-aminophenyl)acridine 
• 30189-59-4 9-(N-methyl-4-aminophenyl)acridine 
• 934472-80-7 9-(4-amino-2,6-dimethoxyphenyl)acridine 
• 934472-79-4 9-(4-amino-2,5-dimethoxyphenyl)acridine 
• 1013398-83-8 9-[4'-N-(N-t-Boc-β-alanyl)aminophenyl]acridine 
• 109277-09-0 9-(4-methanesulphonamidophenyl)acridine 
• 109277-10-3 9-(N-methyl-4-methanesulphonamidophenyl)acridine 

Relevant academic research and scientific papers

Carbon nanotube-acridine nanohybrids: Spectroscopic characterization of photoinduced electron transfer

Single-walled carbon nanotubes (NT) were covalently functionalized with either 9-phenyl acridine (PhA) or 10-methyl-9-phenyl acridinium (PhMeA +). Absorption and fluorescence properties of acridine derivatives tethered to the nanotubes were studied in homogeneous dispersions. Exciplex emission was observed for NT functionalized with 9-phenylacridine. This phenomenon was attributed to an " intramolecular" interaction between excited phenyl acridine and carbon nanotubes. Interestingly, reverse photoinduced electron transfer from the nanotube to 10-methyl-9-phenylacridinium was detected for the NTPhMeA+ nanohybrid. This electron transfer led to a strong quenching of the acridinium fluorescence and to the formation of a metastable acridine radical. Evidence for the formation of this radical was obtained by ESR studies.