177844-94-9Relevant academic research and scientific papers
AN EFFECTIVE SYNTHESIS OF SCALEMIC 3,5,5-TRISUSBSTITUTED PYRROLIN-4-ONES
Smith, Amos B.,Holcomb, Ryan C.,Guzman, Mark C.,Keenan, Terence P.,Sprengeler, Paul A.,Hirschmann, Ralph
, p. 63 - 66 (2007/10/02)
A new two-step method employs the intramolecular cyclization of metalated imino esters for the construction of scalemic 3,5,5-trisubstituted pyrrolin-4-ones (4).The imino esters in turn derive from α-disubstituted amino acids, the latter readily available
