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1H-Pyrazole-4-carboxylic acid, 5-[(4-bromophenyl)methyl]-3-methyl-1-phenyl-, methyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

177846-77-4

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177846-77-4 Usage

Molecular structure

The compound has a complex structure that includes a pyrazole core with substituted phenyl and methyl ester groups.

Biological activity

The compound has potential biological activity and interaction with biological targets.

Pharmaceutical and research applications

The compound is often used in pharmaceutical and research applications due to its potential biological activity.

Drug design and synthesis

The compound is known for its involvement in the design and synthesis of new drugs and drug candidates.

Potential for varied pharmacological activities

The presence of the bromophenyl and methyl ester moieties suggests that 1H-Pyrazole-4-carboxylic acid, 5-[(4-bromophenyl)methyl]-3-methyl-1-phenyl-, methyl ester has the potential for varied pharmacological activities.

Medicinal chemistry

The compound is an interesting target for further investigation and development in the field of medicinal chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 177846-77-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,7,8,4 and 6 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 177846-77:
(8*1)+(7*7)+(6*7)+(5*8)+(4*4)+(3*6)+(2*7)+(1*7)=194
194 % 10 = 4
So 177846-77-4 is a valid CAS Registry Number.

177846-77-4Relevant academic research and scientific papers

PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS

-

, (2008/06/13)

Compounds of general formula I and their salts and solvates are angiotensin II receptor antagonists and as such are useful in the treatment of hypertension, congestive heart failure and elevated intraocular pressure. Pharmaceutical compositions including these compounds and processes for their preparation are also provided.

Synthesis and structure-activity relationship of a new series of potent AT1 selective angiotensin II receptor antagonists: 5-(biphenyl-4- ylmethyl)pyrazoles

Almansa, Carmen,Gómez, Luis A.,Cavalcanti, Fernando L.,De Arriba, Alberto F.,García-Rafanell, Julián,Forn, Javier

, p. 547 - 558 (2007/10/03)

The synthesis and pharmacological activity of a new series of 5- (biphenyl-4-ylmethyl)pyrazoles as potent angiotensin II antagonists both in vitro (binding of [3H]AII) and in vivo (iv, inhibition of AII-induced increase in blood pressure, pithe

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