1779-50-6Relevant academic research and scientific papers
Reaction of thiolesters with nitrogen ylides
Voltrova, Svatava,Srogl, Jiri
, p. 1677 - 1679 (2008)
The pairing of unstabilized nitrogen ylides generated in situ with functionalized thiolesters under ambient conditions resulted in a new intramolecular carbon-carbon bond forming reaction. The scope of the reaction was illustrated with a series of substit
STEREOCHEMICAL OBSERVATIONS ON THE WITTIG REACTION OF OXIDO PHOSPHONIUM YLIDES WITH ALDEHYDES
Maryanoff, Bruce E.,Reitz Allen B.,Duhl-Emswiler, Barbara A.
, p. 2477 - 2480 (2007/10/02)
The reaction of aldehydes with oxido ylides shows a dramatic dependence of alkene stereochemistry on the distance between oxygen and phosphorus atoms; ylides with proximal O and P atoms favor production of E alkenes.The high E stereoselectivity with γ-oxido ylides is not mainly attributable to intramolecular proton-exchange in a Wittig intermediate.
