177980-14-2Relevant academic research and scientific papers
Monomers for oligonucleotide synthesis with linkers carrying reactive residues: II. The synthesis of phosphoamidites on the basis of uridine and cytosine and containing a linker with methoxyoxalamide groups in position 2′
Vasil'eva,Abramova,Ivanova,Shishkin,Sil'nikov
, p. 234 - 242 (2007/10/03)
A convenient preparative synthesis of 2′-amino-2′-deoxyuridine was developed. Starting from 2′-amino-2′-deoxyuridine and 2′-amino-2′-deoxycytidine, monomers for the phosphoamidite oligonucleotide synthesis were obtained that carry a linker with methoxyoxalamide groups in position 2′.
Synthesis of functionally modified oligonucleotides from methoxyoxalamido precursors
Polushin, Nikolai N.
, p. 3231 - 3234 (2007/10/03)
2'-Methoxyoxalamido-2'-deoxyuridine was incorporated into an oligonucleotide molecule and shown to be a useful precursor for the post synthetic introduction of various functional additives.
