177995-52-7

Basic information

• Product Name: 4-(2-Fluoropropan-2-yl)cyclohexanone
• Synonyms: 4-(2-Fluoropropan-2-yl)cyclohexanone
• CAS NO: 177995-52-7
• Molecular Formula: C9H15FO
• Molecular Weight: 158.2132032
• Mol File: 177995-52-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(2-Fluoropropan-2-yl)cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-Fluoropropan-2-yl)cyclohexanone(177995-52-7)
• EPA Substance Registry System: 4-(2-Fluoropropan-2-yl)cyclohexanone(177995-52-7)

Safety Data

• Hazardous Substances Data: 177995-52-7(Hazardous Substances Data)

Upstream product

• 5432-85-9 4-isopropyl-cyclohexanone 

Relevant articles and documents

Functionalization of non-activated C-H bonds in ketones and imines with HF/SbF5/CCl4

Reaction of cyclic ketones 2-6 and imines 15-17 in HF/SbF5 in presence of CCl4 yield hydroxy or fluoroderivatives, hydride abstraction occurring at a site located far from the functional group. Whereas ketones 2-5 yield only hydroxy derivatives, through cyclic carboxonium ion, imines 15, 16 N-protonated in the media conditions give only fluoroderivatives 18, 19, respectively, after quenching with HF-pyridine. Ring contraction is operative when starting from large membered ring ketones 24 and 25, and imine 26, leading to a mixture of hydroxy or fluoro cyclohexanones and/or cycloheptanones.