17802-65-2Relevant academic research and scientific papers
Inspecting the role of synthons in the electronic transition of N-heterocyclic compounds
Guedes, Guilherme P.,Guimar?es, Freddy Fernandes,Maia, Lauro June Queiroz,Martins, Felipe Terra,Valdo, Ana Karoline Silva Mendanha,de Santana, Ricardo Costa
, (2022/03/14)
Intermolecular hydrogen bonding patterns allow us to draw a direct correlation between crystal structure and solid-state properties. To shed more light into the correlation between intermolecular patterns (e.g., synthons) and optical properties, here we prepared eight new crystal forms of template N-heterocyclic compounds. Their synthons were inspected in full detail, as well as the direct band gap of the electronic transitions were determined from their diffuse reflectance spectra and theoretically calculated using TD-DFT. We could find a direct correlation between the synthons strength and the agreement between the theoretical and the experimental electronic transitions, evidencing an important role of the synthons in the electronic transition profile of N-heterocyclic compounds.
A facile and efficient method for the selective deacylation of N-arylacetamides and 2-chloro-Narylacetamides catalyzed by SOCl2
Wang, Gong-Bao,Wang, Lin-Fa,Li, Chao-Zhang,Sun, Jing,Zhou, Guang-Ming,Yang, Da-Cheng
experimental part, p. 77 - 89 (2012/05/20)
Thionyl chloride efficiently and selectively promoted the deacylation of N-arylacetamides and 2-chloro-N-arylacetamides, under anhydrous conditions, without effecting the ester group, aminosulfonyl group, or benzyloxyamide group. This method, which has been successfully applied to a variety of substrates including different N-arylacetamides and 2-chloro-N-arylacetamides, has the attractive advantages of inexpensive reagents, satisfactory selectivity, excellent yields, short reaction time, and convenient workup. This new method can probably be used to selectively deacylate between aromatic amides and alkyl amides. Springer Science+Business Media B.V. 2011.
