17811-38-0

Usage

Occurrence

Naturally found in some plants and fungi, isolated from the roots of Angelica sinensis (dong quai)

Medicinal Properties

Antioxidant: Exhibits antioxidant effects
Anti-inflammatory: Shows anti-inflammatory properties
Cancer Research: Investigated for potential in cancer prevention and treatment

Food Industry Application

Natural Flavoring Agent: Potential as a natural flavoring agent in the food industry

Overall Potential

Promising for various applications in medicine and food science

Upstream product

• 868050-54-8 3-methoxy-2,4-dimethoxycarbonyl-5-(tetrahydropyranyloxymethyl)phenol 
• 868050-59-3 5-hydroxy-7-methoxy-6-methoxycarbonylphthalide 
• 868050-60-6 6-carboxy-5-hydroxy-7-methoxyphthalide 

Relevant academic research and scientific papers

One-pot synthesis of trisubstituted monomethylated benzene-1,3-diols via a Michael addition-Dieckmann cyclization sequence from methyl (E)3-methoxy-4- methoxycarbonylbut-2-enoate anion and methyl alkynoates and its application to the total synthesis of nidulol

The reaction of methyl (E)3-methoxy-4-methoxycarbonylbut-2-enoate (1) with a number of methyl alkynoates under appropriate conditions gave the monomethylated trisubstituted resorcinol derivatives 3 in a regiocontrolled manner, via a Michael addition-Dieckmann cyclization sequence in one pot. The resorcinol 3d, prepared in this manner, was used as the starting material for a three step, highly efficient (54% from 3d) synthesis of the bioactive fungal metabolite nidulol (4). Georg Thieme Verlag Stuttgart.