178161-09-6Relevant academic research and scientific papers
An internal oxidant-directing strategy enabling transition metal-free C–S bond ligation
Zuo, Yingying,Xiong, Feng,Zhao, Jing
, p. 4174 - 4179 (2019)
Organic sulfur compounds have broad applications in biology, medicine and material sciences and intensive efforts have been devoted to developing mild and general C–S bond-forming methods. However, a mild, transition-metal-free, direct C–H bond functionalization method remains elusive. Here, we report the use of an internal oxidant-directing strategy to achieve this goal. The cascade reactions described here show excellent chemoselectivity and a wide substrate scope for both oxyamines and sulfenylation reagents. This study enlarges the synthesis toolbox for preparing structurally diverse sulfilimines under mild conditions.
Phthalimidesulfenyl chloride. x1. a synthetic equivalent of hs+ and+s-s+ species in electrophilic aromatic substitutions
Capozzi, Giuseppe,Falciani, Chiara,Menichetti, Stefano,Nativi, Cristina
, p. 227 - 232 (2007/10/03)
The reaction of phthalimidesulfenyl chloride, 1, with activated arenes provides monosubstituted phthalimidesulfenyl derivatives 3 which can be easily transformed into the corresponding disulfides 7, thiols 8 and masked thiols 9.
