178206-94-5Relevant articles and documents
A novel synthesis of 2,5-dihydropyrrole derivatives as enantiomerically enriched building blocks
Cinquin, Christophe,Bortolussi, Michel,Bloch, Robert
, p. 6943 - 6952 (1996)
A general synthesis of optically active 2,5-dihydropyrroles (3-pyrrolines) substituted at the 2-position by a functionalized chain is described. A highly stereoselective intramolecular Michael reaction afforded the five-membered nitrogen rings with an excellent enantiomeric purity. The unsaturation was generated by a retro Diels-Alder reaction.