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17826-82-3

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17826-82-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 17826-82-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,8,2 and 6 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 17826-82:
(7*1)+(6*7)+(5*8)+(4*2)+(3*6)+(2*8)+(1*2)=133
133 % 10 = 3
So 17826-82-3 is a valid CAS Registry Number.

17826-82-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,4,5-trimethyl-4H-pyrazol-3-one

1.2 Other means of identification

Product number -
Other names 1,3,4-trimethyl-4,5-dihydro-1H-pyrazol-5-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17826-82-3 SDS

17826-82-3Relevant articles and documents

Catch-and-release of HNO with pyrazolones

Guthrie, Daryl A.,Ho, Anthony,Takahashi, Cyrus G.,Collins, Anthony,Morris, Matthew,Toscano, John P.

, p. 1338 - 1348 (2015/02/19)

A new and versatile class of HNO donors, the (hydroxylamino)pyrazolone (HAPY) series of HNO donors utilizing pyrazolone (PY) leaving groups, is described. HNO, the smallest N-based aldehyde equivalent, is used as a reagent along with a variety of PY compounds to synthesize the desired HAPY donors in what can be considered an N-selective HNO-aldol reaction in up to quantitative yields. The bimolecular rate constant of HNO with PY in pH 7.4 phosphate buffer at 37 °C can reach 8 × 105 M-1 s-1. In 1H NMR experiments, the HAPY compounds generate HNO quantitatively (trapped as a phosphine aza-ylide) with half-lives spanning 3 orders of magnitude (minutes to days) under physiologically relevant conditions. B3LYP/6-31G calculations confirm the energetically favorable reactions between HNO and the PY enol and enolate, whereas HNO release is expected to occur through the oxyanion (OHN-PY) of each HAPY compound. HNO has been shown to provide functional support to failing hearts.

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