178268-96-7 Usage
Molecular Structure
1H-Pyrrolo[2,3-b]pyridine, 6-methyl-, 7-oxide (9CI) is an organic compound with a pyridine ring fused to a pyrrole ring, with a methyl group attached at the 6th position, and an oxygen atom at the 7th position, giving it the designation of "7-oxide".
Classification
1H-Pyrrolo[2,3-b]pyridine,6-methyl-,7-oxide(9CI) is a heterocyclic molecule.
Usage
It is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals due to its versatile reactivity and structural diversity.
Biological Activity
It is known for its potential biological activities, making it a promising candidate for drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 178268-96-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,8,2,6 and 8 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 178268-96:
(8*1)+(7*7)+(6*8)+(5*2)+(4*6)+(3*8)+(2*9)+(1*6)=187
187 % 10 = 7
So 178268-96-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H8N2O/c1-6-2-3-7-4-5-9-8(7)10(6)11/h2-5,9H,1H3
178268-96-7Relevant academic research and scientific papers
HETEROCYCLYL SUBSTITUTED PYRROLOPYRIDINES THAT ARE INHIBITORS OF THE CDK12 KINASE
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Page/Page column 73; 74, (2019/04/16)
This invention relates to compounds that are inhibitors of the CDK12 kinase. The compounds are useful in the treatment of disorders mediated by CDK12 kinase including myotonic dystrophy type 1 (DM1) and other disorders caused by the generation of RNA repeat expansion transcripts. In particular,the invention relates to compounds of the formula (I), or a pharmaceutically acceptable salts or N-oxides thereof, wherein R1a, R2, R3, R4a, R4b and R4c are as defined herein.
The synthesis of 4-benzylamino-6-methyl-1H-pyrrolo[3,2-c]pyridine and 4-benzylamino-6-methyl- 1H-pyrrolo[2,3-b]pyridine
Meade, Eric A.,Beauchamp, Lilia M.
, p. 303 - 308 (2007/10/03)
4-Benzylamino-6-methyl-1H-pyrrolo[3,2-c]pyridine (2) and 4-benzylamino-6-methyl-1H-pyrrolo[2,3-b]pyridine (3) were synthesized as deaza analogues of the anxiolytic agent 4-benzylamino-2-methyl-7H-pyrrolo[2,3-d]pyrimidine (1). The 1-deaza analogue (2) was
