178313-80-9Relevant academic research and scientific papers
A combinatorial protecting group strategy for oligonucleotide synthesis
Leikauf, Eckart,Barnekow, Frank,Koester, Hubert
, p. 6913 - 6930 (2007/10/03)
A novel 5'-3' directed DNA synthesis will be described. Together with additional investigations on model compounds a synthetic strategy is established which allows multiselective deprotections. This offers the potential to either generate oligonucleotides in different sequence specific protection/functionalization states or to create a combinatorial set of molecules available for specific molecular interaction of recognition experiments.
