178379-49-2

Upstream product

• 392234-88-7 (1R,3aS,7aR)-1-hydroxymethyl-5-spiro-2'-(1',3'-dioxolane)-7a-methylperhydroinden-3a-ol 
• 178379-37-8 (3aS,7aR)-1-methylen-3a-hydroxy-7a-methylperhydroindene-5-spiro-2'-(1',3'-dioxolane) 
• 178379-36-7 (3aS,7aS)-3a-hydroxy-5-spiro-2'-(1',3'-dioxolane)-7a-methyl-1-perhydroindenone 
• 162240-26-8 C₁₃H₂₀O₄ 
• 178379-39-0 (1S,3aS,7aR)-1-hydroxymethyl-3a-hydroxy-7a-methyl-5-perhydroindenone 
• 87736-74-1 4-(tert-butyldimethylsiloxymethyl)bromobenzene 
• 33879-04-8 (+)-(3aS,7aS)-2,3,3a,4,7,7a-hexahydro-3a-hydroxy-7a-methyl-1H-indene-1,5(6H)-dione 
• 392235-05-1 (1S,3aS,5S,7aR)-1-hydroxymethyl-5-(4-tert-butyldimethylsilyloxymethylphenyl)-7a-methylperhydroinden-3a,5-diol 

Downstream Products

• 178379-48-1 (1S,3aS,5S,7aR)-5-(4-methylphenyl)-3a-hydroxy-7a-methylperhydroindene-1-carboxaldehyde 

Relevant academic research and scientific papers

Synthesis and inotropic activity of 1-(O-aminoalkyloximes) of perhydroindene derivatives as simplified digitalis-like compounds acting on the Na+,K+-ATpase

A series of 5-substituted (3aS,7aR)-7a-methylperhydroinden-3a-o1 derivatives bearing a 1(S)-(ω-aminoalkoxy)iminoalkyl or -alkenyl substituent was synthesized, starting from the Hajos-Parrish ketol 47, as simplified analogues of very potent 17β-aminoalkylo

1,5-disubstituted 7A-methylperhydroinden-3A-ol derivatives, useful in treating cardiovascular disorders, processes for their preparation and pharmaceutical compositions containing the same

1,5-Disubstituted 5a-methylperhydroinden-3a-ol derivatives of formula (I): STR1 where either the symbol - - - - represents a single bond, the group A is in cis configuration with respect to the 3a-hydroxy, 7a-methyl and 1-L groups, and A is (CH=CH)m (CH2)n OR, (CH=CH)m (CH2)n NR1 R2, (CH=CH)m (CH2)p B, OH, O(CH2)q OR, O(CH2)q NR1 R2 or O(CH2)r B; q is an integer from 2 to 5; r is an integer from 1 to 2; or the symbol - - - - represents a double bond, A is oxygen, CH(CH=CH)s (CH2)n OR, CH(CH=CH)s (CH2)n NR1 R2 or CH(CH=CH)s (CH2)p B; and L is ?CH=C(R3)!s CH=NR4 or ?CH=C(R3)!s CH2 NHR4, in the E configuration, are useful for treating cardiovascular disorders such as heart failure and hypertension.