178383-09-0

Basic information

• Product Name: tert-butyl [4-(2-oxo-2-phenylethyl)-2-pyridyl]carbamate
• Synonyms: tert-butyl [4-(2-oxo-2-phenylethyl)-2-pyridyl]carbamate
• CAS NO: 178383-09-0
• Molecular Weight: 312.368
• Mol File: 178383-09-0.mol

Chemical Properties

• CAS DataBase Reference: tert-butyl [4-(2-oxo-2-phenylethyl)-2-pyridyl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl [4-(2-oxo-2-phenylethyl)-2-pyridyl]carbamate(178383-09-0)
• EPA Substance Registry System: tert-butyl [4-(2-oxo-2-phenylethyl)-2-pyridyl]carbamate(178383-09-0)

Safety Data

• Hazardous Substances Data: 178383-09-0(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 695-34-1 2-Amino-4-methylpyridine 
• 21384-41-8 N-benzoyl-2-methylaziridine 
• 90101-20-5 tert-Butyl N-(4-methyl-pyridin-2-yl)carbamate 
• 6919-61-5 N-methoxy-N-methylbenzamide 

Downstream Products

• 365428-83-7 4-(2-ethyl-4-phenyl-1,3-thiazol-5-yl)pyridin-2-amine 

Relevant articles and documents

Novel inhibitor of p38 MAP kinase as an anti-TNF-α drug: Discovery of N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]-2-pyridyl]benzamide (TAK-715) as a potent and orally active anti-rheumatoid arthritis agent

The p38 mitogen-activated protein (MAP) kinase has been implicated in the proinflammatory cytokine signal pathway, and its inhibitors are potentially useful for the treatment of chronic inflammatory diseases such as rheumatoid arthritis (RA) and inflammat

JNK INHIBITOR

The present invention relates to a c-Jun N-terminal kinase inhibitor containing an azole compound (I) substituted by a nitrogen-containing aromatic group having substituent(s)(except a compound represented by the formula: ) or a salt thereof or a prodrug thereof.