1784137-59-2Relevant academic research and scientific papers
BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS
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Page/Page column 288-289; 344, (2021/04/17)
Disclosed are compounds, compositions and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Such compounds are represented by Formula I as follows: Formula I wherein R1, R2, R3, and Q are defined herein.
COMPOUNDS AND USES THEREOF
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Page/Page column 127, (2020/08/22)
The present disclosure features compounds useful for the treatment of BAF complex-related disorders.
Strategy to Prepare 3-Bromo- and 3-Chloropyrazoles
Fox, Richard J.,Schmidt, Michael A.,Eastgate, Martin D.
, p. 2830 - 2839 (2018/03/09)
A general strategy to prepare substituted 3-bromo- and 3-chloropyrazoles is described. The three-step method involves condensation of crotonates or β-chloro carboxylic acids with hydrazines, followed by halogenation and oxidation. Several condensation and oxidation protocols were developed to enable preparation of a wide variety of 3-halopyrazoles with good to excellent yields and regiocontrol.
