178424-02-7Relevant articles and documents
Design, synthesis, and antitumor activity of bicyclic and isomeric analogues of illudin M
Kinder Jr., Frederick R.,Wang, Run-Ming,Bauta, William E.,Bair, Kenneth W.
, p. 1029 - 1034 (1996)
Novel bicyclic and isomeric analogues of the cytotoxic sesquiterpine illudin M were prepared using 1,3-dipolar cycloaddition reactions. Nearly every analogue investigated demonstrated low μM IC50 values when tested in a panel of four human tumor cell lines.