178484-38-3

Upstream product

• 138299-10-2 bis(pivaloyloxymethyl) 1,4-dihydro-1-(methoxymethyl)-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate 
• 138279-10-4 (S)-1-Methoxymethyl-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid mono-(2,2-dimethyl-propionyloxymethyl) ester 

Downstream Products

• 178484-41-8 (R)-5-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-1-methoxymethyl-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester 
• 111495-28-4 (R)-5-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 

Relevant academic research and scientific papers

Asymmetric synthesis of (S)-(+)- and (R)-(-)-NZ-105 through the modified Michaelis-Arbuzov rearrangement as a key step

The asymmetric synthesis of the (S)-(+)- and (R)-(-)-NZ-105 from the prochiral compound (1) was realized by using the modified Hunsdiecker reaction followed by the modified Michaelis-Arbuzov reaction with zerovalent palladium.