178556-45-1Relevant academic research and scientific papers
Discovery of new orally active prostaglandin D2 receptor antagonists
Iwahashi, Maki,Naganawa, Atsushi,Kinoshita, Atsushi,Shimabukuro, Atsushi,Nishiyama, Toshihiko,Ogawa, Seiji,Matsunaga, Yoko,Tsukamoto, Kohki,Okada, Yutaka,Matsumoto, Ryoji,Nambu, Fumio,Oumi, Rie,Odagaki, Yoshihiko,Katagi, Jun,Yano, Koji,Tani, Kousuke,Nakai, Hisao,Toda, Masaaki
experimental part, p. 6935 - 6948 (2012/01/05)
To identify an orally available drug candidate, a series of 3-benzoylaminophenylacetic acids were synthesized and evaluated as prostaglandin D2 (PGD2) receptor antagonists. Some of the compounds tested were found to exhibit excellent
Calcium salts of 1,5-benzodiazepine derivatives, process for producing the salts and drugs containing the same
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, (2008/06/13)
Provided are calcium salts of a 1,5-benzodiazepine derivative represented by the following formula (I): (wherein, R1 represents a lower alkyl group, R2 represents a phenyl or cyclohexyl group, and Y represents a single bond or a lowe
Process for the preparation of nitrobenzene derivatives
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, (2008/06/13)
A method for preparing a compound of formula (I), wherein R1 and R2, which are the same or different, are a hydrogen atom or an alkyl or alkoxy radical, or R1 and R2, taken together with the carbon atom to which
