178666-91-6Relevant academic research and scientific papers
Identification of a 3-hydroxylated tacrine metabolite in rat and man: Metabolic profiling implications and pharmacology
Pool, William F.,Woolf, Thomas F.,Reily, Michael D.,Caprathe, Bradley W.,Emmerling, Mark R.,Jaen, Juan C.
, p. 3014 - 3018 (1996)
Discrepancies in urinary metabolic profiles in rats administered tacrine (1) suggested the presence of an unidentified metabolite of 1. Chromatographic methods were developed that allowed isolation of a metabolite fraction containing both 1-hydroxytacrine
