178686-90-3Relevant academic research and scientific papers
Alkylarylketo acids
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, (2008/06/13)
Disclosed are novel alkylarylketocarboxylic acids and 5-substituted tetrazoles represented by the formula STR1 wherein Z is aryl or an alkyl of the structure STR2 W is a carboxyl moiety or a tetrazole moiety bound to Z at the 5-position of the tetrazole; R1 is C4 -C12 alkyl where Z is aryl and X is oxygen or is C5 -C12 alkyl where Z is alkyl and where Z is aryl and X is a bond; R2 and R3 are each independently hydrogen, C1 -C4 alkyl, hydroxy, C1 -C4 alkoxy, halogen, trihalomethyl, nitro, cyano or C1 -C4 acyl; R4, R5, R6 and R7 are each independently hydrogen or C1 -C4 alkyl or R4 and R6 or R5 and R7 can combine to form a carbocyclic ring; X is oxygen, or a bond at the ortho or para position; m is 0, 1 or 2; and n is 0 or 1, and nontoxic, pharmaceutically acceptable addition salts and carboxylic acid esters thereof.
