178688-10-3Relevant academic research and scientific papers
Synthesis and structure-activity relationships of naphthamides as dopamine D3 receptor ligands
Huang,Luedtke,Freeman,Wu,Mach
, p. 1815 - 1826 (2007/10/03)
A series of naphthamides were synthesized, and the affinities of these compounds were determined for dopamine D2 and D3 receptors using radioligand binding techniques. The naphthamide compounds that were prepared include N-(1- alkylp
Dopamine D3 and D4 receptor antagonists: synthesis and structure--activity relationships of (S)-(+)-N-(1-Benzyl-3-pyrrolidinyl)-5-chloro-4- [(cyclopropylcarbonyl) amino]-2-methoxybenzamide (YM-43611) and related compounds.
Ohmori,Maeno,Hidaka,Nakato,Matsumoto,Tada,Hattori,Sakamoto,Tsukamoto,Usuda,Mase
, p. 2764 - 2772 (2007/10/03)
In this study, we synthesized a series of (S)-N-(3-pyrrolidinyl)benzamide derivatives, 1, 2a-d, 5a-1, and 7, and their enantiomers, (R)-1 and (R)-5c-e, and evaluated their binding affinity for cloned dopamine D2, D3, and D4 receptors and their inhibitory
