17869-27-1Relevant articles and documents
A Precious-Metal-Free Hybrid Electrolyzer for Alcohol Oxidation Coupled to CO2-to-Syngas Conversion
Abdiaziz, Kaltum,Bajada, Mark A.,Reisner, Erwin,Roessler, Maxie M.,Roy, Souvik,Wagner, Andreas,Warnan, Julien
, p. 15633 - 15641 (2020)
Electrolyzers combining CO2 reduction (CO2R) with organic substrate oxidation can produce fuel and chemical feedstocks with a relatively low energy requirement when compared to systems that source electrons from water oxidation. Here, we report an anodic hybrid assembly based on a (2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO) electrocatalyst modified with a silatrane-anchor (STEMPO), which is covalently immobilized on a mesoporous indium tin oxide (mesoITO) scaffold for efficient alcohol oxidation (AlcOx). This molecular anode was subsequently combined with a cathode consisting of a polymeric cobalt phthalocyanine on carbon nanotubes to construct a hybrid, precious-metal-free coupled AlcOx–CO2R electrolyzer. After three-hour electrolysis, glycerol is selectively oxidized to glyceraldehyde with a turnover number (TON) of ≈1000 and Faradaic efficiency (FE) of 83 %. The cathode generated a stoichiometric amount of syngas with a CO:H2 ratio of 1.25±0.25 and an overall cobalt-based TON of 894 with a FE of 82 %. This prototype device inspires the design and implementation of nonconventional strategies for coupling CO2R to less energy demanding, and value-added, oxidative chemistry.
Synthesis of novel phosphoramide-tegafur derivatives containing aminopropylsilatrane
De, Qing Shi,Chen, Qi,Zhong, Hua Li,Xiao, Peng Liu
, p. 1621 - 1627 (2005)
A series of novel phosphoramide-tegafur derivatives containing γ-aminopropyl silatrane were synthesized via the condensation reactions of phosphoryl dichloride with N1-(2-furanidyl)-N3- (hydroxyethyl)-5-fluorouracil, followed by condensation with γ-aminopropyl silatrane. The structures of the products were confirmed by 1H NMR, 31P NMR, IR, MS, and elemental analysis. The results of preliminary bioassay showed that the new compounds had an inhibition effect against HCT-8 and Bel-7402 cell lines. Copyright Taylor & Francis Inc.
Synthesis and reactivity of novel 3-isothiocyanatopropylsilatrane derived from aminopropylsilatrane: X-ray crystal structure and theoretical studies
Singh, Raghubir,Puri, Jugal Kishore,Chahal, Varinder Kaur,Sharma, Raj Pal,Venugopalan, Paloth
, p. 183 - 188 (2010)
A novel silatrane {A figure is presented} containing Si ← N bond (2.160 ?), has been synthesized by the reaction of 3-aminopropylsilatrane (1), dicyclohexylcarbodiimide (2) and CS2. The structure was established by elemental analysis, spectroscopic methods (IR, 1H NMR, 13C NMR and Mass spectroscopy) and X-ray crystallography. It was correlated with theoretical studies such as semiempirical (AM1, PM3, PM3MM and MNDO), Density Functional Theory (B3LYP) and Hartree-Fock at 3-21+G* and 6-31G*(d) levels. The reactivity of compound 3 was studied with some Lewis acids and bases that showed the formation of corresponding adducts (4-7), which were characterized by elemental analysis, IR and NMR (1H, 13C) spectroscopy.
Synthesis, characterization and UV–visible study of schiff base-acetylene functionalized organosilatrane receptor for the dual detection of Zn2+ and Co2+ ions
Devi, Anita,Diksha,Kaur, Jashan Deep,Priyanka,Saini, Anamika,Satija, Pinky,Singh, Gurjaspreet,Suman,Sushma
, (2021)
The present article describes the synthesis of Schiff base-acetylene functionalized organosilatranes (6a–6e) and their characterization by 1H and 13C NMR spectroscopy and ESI-QTOF mass spectrometry. The UV–visible study of the organosilatrane 6a unveiled their high selectivity towards the recognition of Zn2+ and Co2+ ions without exhibiting any significant interference from other competitive metal ions. The calculated value of association constant with 6a for Zn2+ and Co2+ ions was 0.11 × 106 M?1 and 0.24 × 106 M?1 and the limit of detection was 0.28 × 10?6 M and 0.82 × 10?6 M respectively. Furthermore, DFT calculations were performed to get an insight into the interacting behaviour of sensor 6a towards Zn2+ and Co2+ ions.
Synthesis of 1-substituted benzoyl aminopropyl silatranes and their biological activities
Li, Zhonghua,Song, Xiuyan,Su, Huaping,Chen, Jing
, p. 475 - 478 (2005)
Silatranes are organosilicon compounds with outstanding biological activities. Eleven substituted benzoyl aminopropyl silatranes(a-k) have been synthesized by the reaction of aminopropyl silatrane with various substituted benzoyl chlorides. IR, 1HNMR, MS and elemental analysis confirmed their structures. The antibacterial test showed that they were efficient against Fusarium and Rhizataonia.
Silatranes tricyclic shrinkable yang quan type of zinc complex and its synthesis method
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Paragraph 0051; 0053; 0054; 0056, (2019/02/10)
The invention discloses a tricyclic shrinkable yang quan silatranes type of zinc complex and its synthesis method. Synthetic method comprises the following steps: taking three ethanolamine with the γ - amino propyl triethoxy silane reaction, the reaction product through the atmospheric distillation, vacuum distillation, the product to be the middle of the 1st; 1st intermediate product through the anhydrous tetrahydrofuran is dissolved to obtain the 1st dissolved solution, to dissolve water 1st [...] yang quan or 3 substituted salicylaldehyde or 4 substituted salicylaldehyde, reacting at room temperature, precipitated crystals after cooling, through benzene and ethyl ether mixture liquid to separate out of the crystal recrystallize to get heavy crystal, 2nd intermediate product obtained through the purification; taking zinc acetate and anhydrous methanol is dissolved to obtain the 2nd solution, taking 2nd intermediate product using anhydrous tetrahydrofuran solution is dissolved to obtain the 3rd, 2nd 3rd solution with the solution reaction after mixing, separating solid material, be purified of nitrogen and silicon tricyclic shrinkable yang quan type of zinc complex. The synthesis method is low in cost, few by-products and small pollution to the environment.
ETCHANT COMPOSITION, METHOD OF ETCHING INSULATING FILM, METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE, AND SILANE COMPOUND
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Paragraph 0074-0079, (2019/12/06)
An etchant composition includes a silane compound represented by the following Chemical Formula 1: wherein R1 to R6 are independently hydrogen, halogen, a substituted or unsubstituted C1-C20 hydrocarbyl group, a phenyl group, a C1-C20 alkoxy group, a carboxy group, a carbonyl group, a nitro group, a tri (C1-C20) alkylsilyl group, a phosphoryl group, or a cyano group, L is a direct bond or C1-C3 hydrocarbylene, A is an n-valent radical, and n is an integer of 1 to 4.
Synthesis and stimulation of seed germination of γ-aminopropyl silatrane derivatives
Xie, Zi-Xin,Chen, Liang-Fang,Wang, Yue-Wu,Song, Xiao-Qing,Qi, Xiao-Lu,Guo, Ping,Ye, Fa-Qing
, p. 202 - 206 (2014/05/20)
γ-Aminopropyl silatranes have generated wider interests due to their plant growth-regulating activity, safe and demonstrate potential to be plant growth regulators. Therefore, its N-substituted derivatives were synthesized and confirmed by IR, 1H NMR, ESI-MS, and elemental analysis. The seed germination test showed that most compounds possessed better activities of regulating the roots growth on corn (monocotyledon) and radish (dicotyledon) than 1-chloromethylsilatrane (CMS). Moreover, the effect of these compounds was higher at around 10-7 mol/l, while 10-6 mol/l CMS was most efficient.
Silane: A new linker for chromophores in dye-sensitised solar cells
Szpakolski, Katherine,Latham, Kay,Rix, Colin,Rani, Rozina A.,Kalantar-Zadeh, Kourosh
, p. 719 - 732 (2013/06/26)
A series of ruthenium(II) polypyridyl complexes, with novel silane functionalisation, [Ru(bipy)2(bipy-sil)](PF6)2 (3), [Ru(bipy-sil)2Cl2] (6), and [Ru(bipy-sil) 2(NCS)2] (7) have been synthesised and tested as chromophores (dyes) in TiO2 and WO3 based dye-sensitised solar cells (DSSCs). The performance of the respective DSSCs were compared to analogous dyes with ionic carboxylate ([Ru(bipy)2(dcbipy)](PF 6)2 (1), [Ru(dcbipy)2Cl2] (4), [Ru(dcbipy)2(NCS)2] (5)) or phosphonate ([Ru(bipy) 2(dpipy)](PF6)2 (2)) linking groups. The covalent silane-metal oxide linkage offers much needed improvement to the operating conditions, and lifetime of DSSCs, in terms of pH range and choice of solvent. UV-Vis spectroscopy of the deep-red solutions showed that the bis-bipy-sil complexes absorbed more visible light than the tris-bipy complex, as indicated by the presence of two absorption bands and higher ε values. The UV-Vis spectrum of (3) contained a single broad absorption at 400-600 nm with: λmax = 457 nm; ε = 10 520 ± 440 L mol -1 cm-1, whereas two intense broad absorption bands were observed for novel bis-bipy-sil complexes (6): 340-370 nm (λ max(1) = 365 nm, ε(1) = 12 716 ± 180 L mol-1 cm-1); and 440-540 nm (λmax(2) = 485 nm, ε(2) = 11 070 ± 150 L mol-1 cm -1), and (7): 340-400 nm (λmax = 371 nm, ε(1) = 20 690 ± 485 L mol-1 cm-1), and 460-530 nm (λmax = 500 nm and ε(2) = 20 750 ± 487 L mol-1 cm-1). The bands in (7) being significantly more defined. A 10-fold improvement in the efficiency of the bipy-sil TiO2-based DSSCs was observed from (3) to (6) to (7). This performance was lower than that of the commercial N3 dye, [Ru(dcbipy) 2(NCS)2] (5), but the current of (7) on WO3, was comparable to that of the carboxylate system (4). There is considerable potential for further improvement by modification of the silyl linker, reducing the long non-conjugated propyl chain between the amide group and the silatrane (bipy-sil), to a short, conjugated link. During an extensive synthetic study, the most promising strategy was identified as direct linkage, the formation of a direct Si-C bond, using butyllithium with 4,4′-dibromo-2,2′- bipyridine and either trimethylsilane or 1-ethoxysilatrane, provided that the product can be captured and stabilised prior to binding to a metal oxide coated DSSC substrate.
Synthesis and biological evaluation of nucleoside analogues than contain silatrane on the basis of the structure of acyclovir (ACV) as novel inhibitors of hepatitis B virus (HBV)
Han, Anyue,Li, Lingna,Qing, Kuiyou,Qi, Xiaolu,Hou, Leping,Luo, Xintong,Shi, Shaohua,Ye, Faqing
, p. 1310 - 1314 (2013/03/28)
Hepatitis B virus (HBV) infection causes major public health problems worldwide. Acyclovir (ACV) is mainly used to inhibit herpes simplex virus (HSV) rather than HBV. In this study, we used the combination principle to design and synthesize nucleoside analogues that contain silatrane on the basis of the structure of ACV. We found that the compounds were effective inhibitors of HBV, both in vitro and in vivo. All of the compounds showed suppressive activity on the expression of HBV surface antigen (HBsAg) and HBV e antigen (HBeAg) in the HepG2.2.15 cell line with low cytotoxicity. One of compounds was studied in HBV transgenic mice model, and the test results showed its ability to reduce the levels of HBsAg, HBeAg and HBV DNA by ELASE and qPCR. Furthermore, significant improvement of T lymphocyte was observed after treatment, as evaluated by flow cytometry (FCM).
