178694-44-5

Upstream product

• 185989-61-1 C₃₆H₅₁N₃O₈ 
• 178694-40-1 C₄₀H₇₄O₇Si₂ 
• 178694-38-7 Acetic acid (S)-1-[(1S,3R,9S,10R,13S,14R,17S)-1-(tert-butyl-dimethyl-silanyloxy)-3-methoxymethoxy-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-ethyl ester 
• 178694-37-6 Acetic acid (S)-1-[(1S,3R,9S,10R,13S,14R,17S)-1-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-ethyl ester 
• 178694-41-2 1-[(S)-1-((1S,3R,9S,10R,13S,14R,17S)-1-Hydroxy-3-methoxymethoxy-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-ethoxy]-3-methyl-butane-2,3-diol 
• 178694-39-8 (S)-1-[(1S,3R,9S,10R,13S,14R,17S)-1-(tert-Butyl-dimethyl-silanyloxy)-3-methoxymethoxy-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-ethanol 
• 103909-74-6 1-[1,3-bis-(tert-butyldimethylsilanyloxy)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanol 
• 4233-33-4 4-Phenyl-1,2,4-triazolidine-3,5-dione 
• 178694-43-4 C₃₆H₄₉N₃O₈ 
• 178694-36-5 Acetic acid (S)-1-[(1S,3R,9S,10R,13S,14R,17S)-1,3-bis-(tert-butyl-dimethyl-silanyloxy)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-ethyl ester 

Relevant academic research and scientific papers

Synthetic studies of vitamin D analogs. XXII. Synthesis and antiproliferation activity of putative metabolites of 1α,25-dihydroxy-22-oxavitamin D3

As putative metabolites of 1α,25-dihydroxy-22-oxavitamin D3 (OCT), 24-hydroxylated OCT in 24(R) and 24(5) forms, 24-ketoOCT, 26-hydroxylated OCT in 25(S) and 25(R) forms, pentanorOCT and pentanor-ketoOCT were synthesized from the steroidal 20(S)-alcohol. Their antiproliferation activities towards human promyelocytic leukemia cells (HL-60 cells) are also reported. Oxidized derivatives at the C-24 position, 24-ketoOCT, 24(R)-hydroxylated OCT and 24(S)-hydroxylated OCT, showed activities comparable to or slightly weaker than that of OCT, while 26-hydroxylated OCT was less active than OCT. Truncated OCT, pentanor OCT and pentanor-ketoOCT, were inactive at 10-7-10-10M.