178809-76-2

Basic information

• Product Name: (4-Nitro-phenyl)-(1-oxy-pyridin-4-yl)-methanol
• CAS NO: 178809-76-2
• Molecular Weight: 246.222
• Mol File: 178809-76-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-Nitro-phenyl)-(1-oxy-pyridin-4-yl)-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Nitro-phenyl)-(1-oxy-pyridin-4-yl)-methanol(178809-76-2)
• EPA Substance Registry System: (4-Nitro-phenyl)-(1-oxy-pyridin-4-yl)-methanol(178809-76-2)

Safety Data

• Hazardous Substances Data: 178809-76-2(Hazardous Substances Data)

Upstream product

• 39055-88-4 (4-nitrophenyl)(pyridin-4-yl)methanone 
• 178809-75-1 4-(1-hydroxy-1-(4-pyridyl)methyl)-1-nitrobenzene 

Relevant articles and documents

Hydroxide-promoted redox reactions in water of α-phenyl-4-nitrobenzenemethanol, α-(p-nitrophenyl)-4-pyridinemethanol, and α-(p-Nitrophenyl)-4-pyridinemethanol N-oxide steric inhibition of resonance

α-Phenyl-4-nitrobenzenemethanol (3) reacted with 1 M sodium hydroxide to yield 4,4′-dibenzoylazoybenzene (5) (51%), 4-hydroxy-4′-benzoylazobenzene (6) and benzoic acid (12% each), and smaller amounts of 4-aminobenzophenone and 4-nitrobenzophenone. Both α-phenyl-2-nitrobenzenemethanol (9) and 3,5-dimethyl-4-nitrobenzenemethanol (10a) did not react with 1 M sodium hydroxide, presumably due to steric hindrance. α-(p-Nitrophenyl)-4-pyridinemethanol (14) and its N-oxide 11 with 1 M sodium hydroxide yielded 4,4′-diaroylazoxybenzenes 15a and 12a, respectively, 4,4′-diaroylazobenzenes 15b and 12b, respectively, as well as 4-hydroxy-4′-aroylazobenzenes 16 and 13, respectively. The relative reaction rates were 11 > 14 > 3. Studies with 11 showed that the nitro group is involved in the redox reaction in preference to the N-oxide group.