17894-26-7

Usage

Uses

Used in Pharmaceutical Industry:
2,5-Dimethoxy-3-nitrobenzoic acid is used as an intermediate in the synthesis of various pharmaceutical compounds for [application reason]. Its unique chemical structure allows it to be a key component in the development of new drugs targeting specific medical conditions.
Used in Chemical Research:
In the field of chemical research, 2,5-Dimethoxy-3-nitrobenzoic acid is used as a research compound for [application reason]. Its properties and reactivity are studied to understand its potential applications in the development of new materials, catalysts, or other chemical products.
Used in Dye Industry:
2,5-Dimethoxy-3-nitrobenzoic acid is used as a starting material in the production of dyes for [application reason]. Its chemical structure can be modified to create a range of colors, making it valuable in the dye industry for creating new and vibrant dyes.
Used in Material Science:
In material science, 2,5-Dimethoxy-3-nitrobenzoic acid is used as a component in the development of advanced materials for [application reason]. Its properties may contribute to the creation of materials with specific characteristics, such as improved strength, durability, or chemical resistance.

InChI:InChI=1/C9H9NO6/c1-15-5-3-6(9(11)12)8(16-2)7(4-5)10(13)14/h3-4H,1-2H3,(H,11,12)/p-1

Upstream product

• 74422-90-5 2,5-dimethoxy-3-nitrobenzaldehyde 
• 2785-98-0 2,5-dimethoxybenzoic acid 
• 7697-37-2 nitric acid 
• 17894-27-8 methyl 2,5-Dimethoxy-3-nitrobenzoate 

Downstream Products

• 125138-14-9 3-amino-2,5-dimethoxybenzoic acid 
• 1220387-60-9 C₂₈H₂₉N₃O₁₂ 
• 1220387-59-6 C₂₇H₂₇N₃O₁₁ 
• 1220387-57-4 C₁₉H₂₀N₂O₉ 

Relevant academic research and scientific papers

Synthesis, structural investigations, hydrogen-deuterium exchange studies, and molecular modeling of conformationally stablilized aromatic oligoamides

Biasing the conformational preferences of aromatic oligoamides by internally placing intramolecular hydrogen bonds has led to a series of stably folded molecular strands. This article presents the results from extensive solid-state, solution, and computational studies on these folding oligomers. Depending on its backbone length, an oligoamide adopts a crescent or helical conformation. Surprisingly, despite the highly repetitive nature of the backbone, the internally placed, otherwise very similar intramolecular hydrogen bonds showed significantly different stabilities as demonstrated by hydrogen-deuterium exchange data. It was also observed that the hydrogen-bonding strength can be tuned by adjusting the substituents attached to the exterior of the aromatic backbones. Examining the amide hydrogen-deuterium exchange rates of trimers revealed that a six-membered hydrogen bond nearing the ester end is the weakest among all the four intramolecular hydrogen bonds of a molecule. This observation was verified by ab initio quantum mechanical calculations at the level of B3LYP/6-31G. Such a "weak point" creates the "battle of the bulge" where backbone twisting is centered, which is consistently observed in the solid-state structures of the four trimer molecules studied. In the solid state, the oligomers assemble into interesting one-dimensional structures. A pronounced columnar packing of short oligomers (i.e., dimers, trimers, and tetramer) and channel-like, potentially ion-conducting stacks of longer oligomers (i.e., tetramer, pentamer, and hexamer) were observed.

Synthesis of a pyrrolo[1,4]benzodiazepinequinone

Condensation of 3,6-dimethoxy-2-nitrobenzoyl chloride with L-proline methyl ester afforded amide 4, which underwent reductive cyclization with iron(II) sulfate and ammonium hydroxide to yield pyrrolobenzodiazepine 5. Oxidation of 5 with ammonium cerium(IV