17894-38-1Relevant articles and documents
Efficient copper-catalyzed amination of DNA-conjugated aryl iodides under mild aqueous conditions
Ruff, Yves,Berst, Frédéric
supporting information, p. 1188 - 1193 (2018/08/01)
Herein, we describe the development of copper-catalyzed cross-coupling of DNA-conjugated aryl iodides with aliphatic amines. This protocol leverages a novel ligand, 2-((2,6-dimethoxyphenyl)amino)-2-oxoacetic acid, to effect the transformation in aqueous D
Oxanilic acids, a new series of orally active antiallergic agents
Sellstedt,Guinosso,Begany,Bell,Rosenthale
, p. 926 - 933 (2007/10/05)
A large number of oxanilic acid esters and N heteroaryl oxamic acid esters were prepared and found to have antiallergic activity using the rat passive cutaneous anaphylaxis (PCA) test. Many of the oxanilic acid esters are active orally, with the most active species having an aryl 2' carbamoyl group and a 3' methoxy group. Hydrolysis of the ester from the oxanilic ester moiety causes a loss of oral activity.