178972-31-1Relevant articles and documents
Monocharged inhibitors of mast cell tryptase derived from potent and selective dibasic inhibitors
Dener, Jeffrey M,Wang, Vivian R,Rice, Kenneth D,Gangloff, Anthony R,Kuo, Elaine Y.-L,Newcomb, William S,Putnam, Daun,Wong, Martin
, p. 2325 - 2330 (2001)
Truncation of potent and selective dibasic inhibitors afforded monocharged inhibitors of human mast-cell tryptase. Using two classes of analogues as lead structures, several monocharged derivatives were identified with Ki values ranging from 0.
