178982-67-7Relevant academic research and scientific papers
FUNGICIDAL HETEROCYCLIC COMPOUNDS
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Page/Page column 44, (2010/11/24)
A compound which can specifically or selectively expresses an antifungal activity with a broad spectrum, based on the functional mechanism of 1,6-β-glucan synthesis inhibition, is provided, and an antifungal agent which comprises such a compound, a salt thereof or a solvate thereof is provided. A compound represented by the following formula (I), a salt thereof or a solvate thereof.
SULPHUR-LINKED IMIDAZOLE COMPOUNDS FOR THE TREAMENT OF HIV
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Page/Page column 50, (2010/02/14)
This invention relates to isophthalonitrile derivatives of formula (I) or pharmaceutically acceptable salts, solvates or derivative thereof, wherein R1 to R3 are defined in the description, and to processes for the preparation thereof, intermediates used in their preparation of, compositions containing them and the uses of such derivatives.The compounds of the present invention bind to the enzyme reverse transcriptase and are modulators, especially inhibitors thereof.
Process for producing arylsulfenyl halide
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Page/Page column 13, (2010/11/29)
A process for producing a compound of the formula (II): wherein Hal1 represents halogen and R1 and R2 each independently represents halogen, alkyl, alkoxy, nitro or cyano, which comprises allowing a halogenating agent to react with a compound of the formula (I): wherein Alk represents branched alkyl and R1 and R2 are as defined above.
Process for producing imidazole derivatives
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, (2008/06/13)
PCT No. PCT/JP97/04708 Sec. 371 Date Jun. 10, 1999 Sec. 102(e) Date Jun. 10, 1999 PCT Filed Dec. 19, 1997 PCT Pub. No. WO98/29395 PCT Pub. Date Jul. 9, 1998The present invention provides a process for producing a compound of the formula (III): wherein R1 and R3 are independently hydrogen or an organic group; R2 is an organic group; and R4 is an optionally substituted aryl. by reacting the compound of formula (I): wherein R1, R2, and R3 are as defined above, with the compound of formula (II):R4-S-Hal(II)wherein R4 is as defined above and Hal is halogen, in the presence of base.
Imidazole derivatives as anti-HIV agents
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, (2008/06/13)
An imidazole derivative represented by general formula (I) or a salt thereof, having the effect of specifically inhibiting the growth of HIV as a pathogenic virus and being reduced in toxicity. In said formula R1 represents hydrogen, C1 -C20 alkyl, C2 -C7 alkenyl, C4 -C12 cycloalkylalkyl, etc.; R2 represents C1 -C6 alkyl, C1 -C6 acyl, hydroxyiminomethyl, hydrazonomethyl or --(CH2)n--R4 (R4 being halogeno, alkoxy, hydroxy, etc.; and n being an integer of 1 to 3); R3 represents substituted or unsubstituted C1 -C6 alkyl; X and Y represent each independently hydrogen, C1 -C3 alkyl, halogeno, or nitro; and Z represents S, SO, SO2 or CH2. STR1
