179018-52-1

Basic information

• Product Name: 1-[2-[4-(2-phenylethenyl)phenoxy]ethyl]pyrrolidine
• Synonyms: 1-[2-[4-(2-phenylethenyl)phenoxy]ethyl]pyrrolidine
• CAS NO: 179018-52-1
• Molecular Weight: 293.409
• Mol File: 179018-52-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-[2-[4-(2-phenylethenyl)phenoxy]ethyl]pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-[4-(2-phenylethenyl)phenoxy]ethyl]pyrrolidine(179018-52-1)
• EPA Substance Registry System: 1-[2-[4-(2-phenylethenyl)phenoxy]ethyl]pyrrolidine(179018-52-1)

Safety Data

• Hazardous Substances Data: 179018-52-1(Hazardous Substances Data)

Upstream product

• 6554-98-9 trans-4-Hydroxystilbene 
• 7250-67-1 1-(2-chloroethyl)pyrrolidine hydrochloride 

Relevant articles and documents

LTA4 Hydrolase inhibitors

The present invention provides compounds of the formula Ar1-Q-Ar2-Y-R-Z and pharmaceutically acceptable salts thereof wherein Ar1 and Ar2 are optionally substituted aryl moieties, Z is an optionally substituted nitrogen-containing moiety which may be an acyclic, cyclic or bicyclic amine or an optionally substituted monocyclic or bicyclic nitrogen-containing heteroaromatic moiety; Q is a linking group capable of linking two aryl groups; R is an alkylene moiety; Y is a linking moiety capable of linking an aryl group to an alkylene moiety and wherein Z is bonded to R through a nitrogen atom. The compounds and pharmaceutical compositions of the present invention are useful in the treatment of inflammatory diseases which are mediated by LTB4 production, such as proriasis, ulcerative colitis, IBD and asthma.

LTA4 HYDROLASE INHIBITOR PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE

The present invention provides compounds of the formula Ar1-Q-Ar2-Y-R-Z and pharmaceutically acceptable salts thereof wherein Ar1 and Ar2 are optionally substituted aryl moieties, Z is an optionally substituted nitrogen-containing moiety which may be an a