179093-97-1Relevant academic research and scientific papers
Stereochemical control of N,N-disubstitution in alkynylaminocarbene complexes of chromium(O) and tungsten(O)
Sabaté, Ramon,Schick, Ute,Moretó, Josep M.,Ricart, Susagna
, p. 3611 - 3615 (1996)
Stereocontrol in the introduction of substituents on the nitrogen of alkynylaminocarbene complexes can be achieved by a proper sequential aminolysis of the starting alkoxy carbene analogs followed by treatment of the resulting (E-alkylamino)carbene complex with Cs2CO3 in the presence of the desired electrophile. The use of Cs2CO3 as a base affords good yields of N,N-disubstituted alkynylcarbene complexes. The isomerization described for other systems was avoided in this case. The reaction is also applicable to bulky electrophiles like (-)-myrtenyl or (-)-perillyl bromides and also to arylcarbene complexes.
