179117-27-2

Upstream product

• 34585-11-0 chloro-(1-naphthalenyl)-phenylphosphine 
• 644-97-3 Dichlorophenylphosphine 
• 703-55-9 1-naphthylmagnesiumbromide 
• 36043-00-2 dichloro(naphthalen-1-yl)phosphane 

Downstream Products

• 1579997-22-0 C₃₄H₂₅O₂PS 
• 1579997-09-3 C₃₄H₂₅O₂P 
• 1579997-09-3 C₃₄H₂₅O₂P 
• 1579997-09-3 C₃₄H₂₅O₂P 

Relevant academic research and scientific papers

An expedient reduction of sec-phosphine oxides to sec-phosphine-boranes by BH3·SMe2

Secondary phosphine oxides can be expeditiously converted into secondary phosphine-boranes by treatment with an excess of BH3·SMe2 at room temperature. Selectivity of the conversion towards the formation of secondary phosphine-boranes is greatly improved by the addition of a small amount of water to the reaction mixture.

Asymmetric synthesis of P -stereogenic diarylphosphinites by palladium-catalyzed enantioselective addition of diarylphosphines to benzoquinones

The reaction of phenyl(2,4,6-trimethylphenyl)phosphine with a substituted benzoquinone in the presence of a chiral phosphapalladacycle complex as a catalyst and triethylamine in chloroform at -45 °C proceeded in a new type of addition manner to give a high yield of a 4-hydroxyphenyl phenyl(2,4,6-trimethylphenyl)phosphinite with 98% enantioselectivity, which is a versatile intermediate readily convertible into various phosphines and their derivatives with high enantiomeric purity.

Preparation of chiral phosphorus, sulfur and selenium containing 2-aryloxazolines

A series of enantiomerically pure 2-[2-(diarylphosphino)aryl]-oxazolines was prepared from commercially available or synthetic amino alcohols. For oxazoline formation three procedures were employed: (i) one pot condensation with a 2-halobenzoic acid (ii) ZnCl2 catalyzed condensation with a 2-halobenzonitrile, and (iii) a three step sequence via a 2-halobenzamide and a tosylate or chloride. Phosphinooxazolines containing stereogenic phosphorous were prepared by either diastereoselective nucleophilic substitution of halogenide of Ar1Ar2PCl or by nucleophilic aromatic substitution with LiPAr1Ar2. In addition, sulfur and selenium analogs were prepared.