179184-45-3Relevant academic research and scientific papers
A synthetic route to (±)-clavizepine through a dibenzoxepine intermediate
De La Fuente,Castedo, Luis,Dominguez, Domingo
, p. 5818 - 5822 (2007/10/03)
A new synthesis of (±)-clavizepine (1a), based on the dibenzoxepinediol 16 as main intermediate is described. The key step is the contraction of the oxepine ring to give the xanthene-9-carboxyaldehyde 11, on which the nitrogenated ring can be readily assembled.
