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179235-07-5

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179235-07-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 179235-07-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,2,3 and 5 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 179235-07:
(8*1)+(7*7)+(6*9)+(5*2)+(4*3)+(3*5)+(2*0)+(1*7)=155
155 % 10 = 5
So 179235-07-5 is a valid CAS Registry Number.

179235-07-5Upstream product

179235-07-5Downstream Products

179235-07-5Relevant articles and documents

INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

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, (2008/06/13)

The present invention comprises analogs of the CAAX motif of the protein Ras that is modified by farnesylation in vivo. These CAAX analogs inhibit farnesyl-protein transferase. Furthermore, these CAAX analogues differ from those previously described as inhibitors of farnesyl-protein transferase in that they do not have a thiol moiety. The lack of the thiol offers unique advantages in terms of improved pharmacokinetic behavior in animals, prevention of thiol-dependent chemical reactions, such as rapid antoxidation and disulfide formation with endogenous thiols, and reduced systemic toxicity. Further contained in this invention are chemotherapeutic compositions containing these farnesyl transferase inhibitors and methods for their production.

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