179239-03-3Relevant academic research and scientific papers
Microbial reduction of α,α,α-trifluoro-α′-sulfenylketones
Arnone, Alberto,Biagini, Giuditta,Cardillo, Rosanna,Resnati, Giuseppe,Begue, Jean-Pierre,Bonnet-Delpon, Daniele,Kornilov, Andrei
, p. 3903 - 3906 (2007/10/03)
Several microorganisms have been employed in the reduction of two α,α,α-trifluoro-α′-sulfenylketones. Some of them produce corresponding alcohols in high diastero-and enantioselection, the high conversion in a single enantiomer being secured by the racemization of starting ketones in the biotransformation conditions. Transformation of obtained sulfenyl-trifluoromethyl-alcohols into trifluoromethyl-epoxides is also described. Copyright
